The following links are for Federal Electronic Submission systems:

NSF -FASTLANE

https://www.fastlane.nsf.gov/fastlane.jsp

NIH-ERA COMMONS

https://commons.era.nih.gov/commons/

GRANTS.GOV

http://www.grants.gov/

U.S. DEPARTMENT OF EDUCATION E-GRANTS

http://www2.ed.gov/fund/grants-apply.html

CORPORATION FOR NATIONAL AND COMMUNITY SERVICE- E-GRANTS

https://egrants.cns.gov/espan/main/login.jsp

Several of these, such as Fastlane and ERA Commons require that individuals be registered before they can submit grants, so contact the Grants Office (x50394) for assistance.