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Amy C. Groth

Associate Professor

Dr. Groth has studied genetic engineering, gene therapy, gene regulation, cancer and development. She earned a B.S. in Molecular Biology from U.C. San Diego and a Ph.D. from Stanford University in Cancer Biology. She has also conducted postdoctoral research in the Medical Genetics Department at the University of Washington, Seattle and in the Biochemistry Department at the University of Wisconsin, Madison.

Research Interests
  • Gene regulation pathways in cancer and development
  • Model organisms/C. elegans
Of Note

Dr. Groth was the 2016 Biology Department Mentor of the Year. She has worked with a dozen undergraduate research students in the past five years, many of whom are currently in graduate school, medical school, nursing school or working in the biotechnology industry.

Teaching Interests
  • Biotechnology
  • Biology of Cancer
  • Genetics

Groth AC. Using C. elegans Notch Mutants in an Undergraduate Cancer Biology Laboratory Course to Demonstrate Oncogenic Effects on Cell Proliferation J Biol Edu. 2018 (In press)

Groth AC, Liu M, Wang H, Lovelett E, Emery DW. Identification and characterization of enhancer-blocking insulators to reduce retroviral vector genotoxicity. PLoS One. 2013 Oct 3;8(10):e76528.

Groth AC, Fish M, Nusse R, Calos MP. Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31. Genetics. 2004 Apr;166(4):1775-82.

Groth AC, Olivares EC, Thyagarajan B, Calos MP. A phage integrase directs efficient site-specific integration in human cells. Proc Natl Acad Sci USA. 2000 May 23;97(11):5995-6000.

Thyagarajan B, Guimarães MJ, Groth AC, Calos MP. Mammalian genomes contain active recombinase recognition sites. Gene. 2000