Syllabus

 

DNA/RNA structure and topology

Large-scale organization,

DNA melting, hybridization, cot1/2, repetitive DNA

Restriction enzymes, mapping, plasmids, transformation

Genome packaging

DNA replication: topology of replication, enzymology

Recombination

Gene function

Genetic code

TranscriptionI , Transcription II, Modifications

Translation and post-translational modifications

Regulation: bacterial, viral, eukaryotic, epigenetics

RNAi, small non-transcribed RNAs

Mutation, repair Selection

Transposons