Adams
Topics may not fit exactly in the time slots listed. To access the Scitable readings, look at the hand out you received at the first class for details.
'Slides' links to PDF files that contain a copy of the slides used in lecture.
The lab titles are linked to PDF handouts for each of the labs.
NOTE: Each chapter in the book has additional readings listed on the right hand side of each page. You are expected to read these, in addition to the basic information.
Date |
Topic |
Text |
Scitable |
Slides |
Lab ( Tuesdays) |
Jan 14 M |
Introduction, History | 45,13 |
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||
16 W |
DNA structure I | 45,13 | 1.1, 1.2, 1.3 | ||
18 F |
DNA Structure II, | 45,13 | 2.1 | ||
21 M |
No class | ||||
23 W |
Genome structure | 48, 63 | 2.2 | ||
25 F |
DNA Replication I | 48 | 2.3, 2.4 | ||
28 M |
DNA Replication II, Telomeres | 46,3 | 3.4, 3.1 |
|
|
30 W |
Gene Function | 49 | 3.2, 3.3 | ||
Feb 1 F |
Genetic Code | 49 | 4.1, 4.2 | ||
4 M |
RNA | 50,62 | 4.3, 4.4 |
|
|
6 W |
Transcription I | 50 | 5.1 | ||
8 F |
Transcription II | 50 | 5.2, 5.3 | ||
11 M |
Translation I | 51 | 6.1, 6.2 |
Attend Job seminar |
|
13 W |
Exam I | ||||
15 F |
No class | 52 | |||
18 M |
No class | 53,54 |
|
||
20 W |
Translation II | 51 | 6.3, 6.4 | ||
22 F |
Regulation I | 52 | 7.1, 7.2 | ||
25 M |
Regulation II | 53,54 | 7.3 |
|
|
27 W |
Mutation | 47 | 8.1,8.2 | ||
Mar 1 F |
Repair | 47 | 8.3 | ||
4 M |
Biotechnology I | 58,59 | 9.1, 9.2 |
|
|
6W |
Biotechnology II | 60,61 | 9.3,9.4 | ||
8 F |
Biotechnology III | 61,62 | 9.5,9.6 | ||
11 M |
Exam 2 |
Scitable readings
| 1.1 Introduction: What Is DNA? 1.2 Discovery of the Function of DNA Resulted from the Work of Multiple Scientists 1.3 Developing the chromosome theory |
2.1 DNA is a structure that encodes biological information 2.2 Discovery of the function of DNA 2.3 Chemical structure of RNA 2.4 DNA packaging |
3.4 DNA replication: overview 3.2 Semi-conservative DNA replication 3.2 Major molecular events of DNA replication 3.3 Telomeres and telomerase |
4.1 Discovering the relationship between DNA and protein 4.2 Reading the genetic code 4.3 What is a gene? 4.4 Nucleic acids to amino acids |
5.1 DNA transcription 5.2 RNA transcription by RNA polymerase 5.3 RNA splicing |
6.1 Translation: DNA to mRNA to protein 6.2 The role of ribosomes 6.3 Translation 6.4 Protein folding |
7.1 Overview 7.2 Negative transcription regulation 7.3 Positive transcription control |
8.1 DNA replication and causes of mutation 8.2 Genetic mutation 8.3 Environmental mutagens |
9.1 Plasmids 9.2 Restriction enzymes 9.3 Recombinant DNA 9.4 Animal cloning 9.5 Cell culture 9.6 Gene-based therapeutics |
M |
Mar |
11 |
Mitosis/Meiosis
|
|
W |
|
13 |
Mendel |
|
F |
|
15 |
Mendel |
|
M |
|
18 |
Departures from Mendel |
VGL |
W |
|
20 |
Departures from Mendel |
|
F |
|
22 |
Departures from Mendel |
|
M |
|
25 |
Vacation |
NO LAB |
W |
|
27 |
Vacation |
|
F |
|
29 |
Vacation |
|
M |
Apr |
1 |
Hardy-Weinberg Equilibrium |
DNA extraction PCR |
W |
|
3 |
Hardy-Weinberg Equilibrium |
|
F |
|
5 |
Natural Selection |
|
M |
|
8 |
Natural Selection |
Gel Electrophoresis |
W |
|
10 |
Natural Selection |
|
F |
|
12 |
Genetic Drift |
|
M |
|
15 |
Genetic Drift |
Writing Lab |
W |
|
17 |
Genetic Drift |
|
F |
|
19 |
Gene Flow |
|
M |
|
22 |
Gene Flow |
Comprehensive Exam |
W |
|
24 |
Gene Flow |
|
F |
|
26 |
Inbreeding |
|
PM |
|
29 |
Inbreeding |
Population Structure and Inbreeding |
W |
May |
1 |
Inbreeding |
|
Final |
|
|
|
Lab handouts
Mitosis/Meiosis
Scitable Outline
Mitosis and Meiosis
Mitosis and Cell Division
Meiosis, Genetic Recombination, and Sexual Reproduction
Mendelian Genetics
Gregor Mendel and the Principles of Inheritance
Mendelian Genetics: Patterns of Inheritance and Single-Gene Disorders
Modifications of Mendelian Genetics
Discovery and Types of Genetic Linkage
Pleiotropy: One Gene Can Affect Multiple Traits
Epistasis: Gene Interaction and Phenotype Effects
Genetic Variation & Hardy-Weinberg Equilibrium
Sexual Reproduction and the Evolution of Sex
Neutral Theory: The Null Hypothesis of Molecular Evolution
HWE Violations: Natural Selection
Negative Selection
Natural Selection: Uncovering Mechanisms of Evolutionary Adaptation to Infectious Disease
HWE Violations: Mutation
Genetic Mutation
HWE Violations: Drift
Genetic Drift and Effective Population Size
Genetic Drift: Bottleneck Effect and the Case of the Bearded Vulture
HWE Violations: Gene Flow
Hybridization and Gene Flow
Why Should We Care about Species?