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Adams
Topics may not fit exactly in the time slots listed. To access the Scitable readings, look at the hand out you received at the first class for details.
The PDF files contain a copy of the slides used in lecture.
The lab titles are linked to PDF handouts for each of the labs.
Date |
Topic |
Text |
Scitable |
Slides |
Lab (Tuesdays) |
Jan 25 M |
Introduction | Orientation. Techniques |
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27 W |
History. Genes are DNA | 14.1, 4 | 1.1, 1.2, 1.3 | ||
29 F |
DNA structure I | 14 | 2.1 | ||
Feb 1 M |
DNA Structure II | 14 | 2.2 | ||
3 W |
Genome structure. RNA | 14 | 2.3, 2.4 | ||
5 F |
DNA Replication I | 14 | 3.1, 3.2 | ||
8 M |
DNA Replication II | 14 | 3.3 | ||
10 W |
Telomeres | 14 | 3.4 | ||
12 F |
Vacation | ||||
15 M |
Vacation | Library. Writing |
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17 W |
Gene Function | 15 | 4.1, 4.2 | ||
19 F |
Genetic Code | 15 | 4.3, 4.4 | ||
22 M |
Transcription I | 16 | 5.1 | ||
24 W |
Transcription II | 16 | 5.2, 5.3 | ||
26 F |
Exam I. To Feb 20 | ||||
Mar 1 M |
Translation I | 16 | 6.1, 6.2 | ||
3 W |
Translation II | 16 | 6.3, 6.4 | ||
5 F |
Regulation I | 17 | 7.1, 7.2 | ||
8 M |
Regulation II | 18 | 7.3 | ||
10 W |
Mutation | 14.5 | 8.1, 8.2 | ||
12 F |
Repair | 14.5 | 8.3 | ||
15 M |
Biotechnology I | 19/20 | 9.1, 9.2 | Lab exam |
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17 W |
Biotechnology II | 19/20 | 9.3, 9.5 | ||
19 F |
Biotechnology III * | 19/20 | 9.4, 9.6 |
* The last lecture may become the second exam
Scitable readings
| 1.1 Introduction: What Is DNA? 1.2 DNA Is a Structure That Encodes Biological Information 1.3 Discovery of the Function of DNA Resulted from the Work of Multiple Scientists |
2.1 DNA is a structure that encodes biological information 2.2 Discovery of the function of DNA 2.3 Chemical structure of RNA 2.4 DNA packaging |
3.1 DNA replication: overview 3.2 Semi-conservative DNA replication 3.3 Major molecular events of DNA replication 3.4 Telomeres and telomerase |
4.1 Discovering the relationship between DNA and protein 4.2 Reading the genetic code 4.3 What is a gene? 4.4 Nucleic acids to amino acids |
5.1 DNA transcription 5.2 RNA transcription by RNA polymerase 5.3 RNA splicing |
6.1 Translation: DNA to mRNA to protein 6.2 The role of ribosomes 6.3 Translation 6.4 Protein folding |
7.1 Overview 7.2 Negative transcription regulation 7.3 Positive transcription control |
8.1 DNA replication and causes of mutation 8.2 Genetic mutation 8.3 Environmental mutagens |
9.1 Plasmids 9.2 Restriction enzymes 9.3 Recombinant DNA 9.4 Animal cloning 9.5 Cell culture 9.6 Gene-based therapeutics |
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| Date | Topic | Text | Scitable | Lab |
| M 3/29 | Mitosis | 11 | Mitosis & Meiosis | |
| 3/31 | Meiosis | 12 | ||
| M 4/5 | Meiosis | 12 | Intro to Probability | |
| 4/7 | Mendelian Genetics | 13 | ||
| 4/9 | Mendelian Genetics | 13 | ||
| M 4/12 | Mendelian Genetics | 13 | Mendelian Genetics Problems | |
| 4/14 | Modifications of Mendelian Genetics | 13 | ||
| 4/16 | Modifications of Mendelian Genetics | 13 | ||
| M 4/19 | Genetic Variation | 24 | DNA extraction & PCR | |
| 4/21 | Hardy-Weinberg Equilibrium | 24 | ||
| 4/23 | Hardy-Weinberg Equilibrium | 24 | ||
| M 4/26 | HWE Violations:Natural Selection | 24 & 25 | Electrophoresis | |
| 4/28 | HWE Violations:Natural Selection | 25 | ||
| 4/30 | HWE Violations:Natural Selection | 25 | ||
| M 5/3 | HWE Violations:Mutation | 25 | Writing Lab | |
| 5/5 | HWE Violations:Drift | 25 | ||
| 5/7 | HWE Violations:Drift & Gene Flow | 25 | ||
| M 5/10 | HWE Violations:Gene flow & inbreeding | 25 | Evolution Simulations | |
| 5/12 | HWE Violations:Gene flow & inbreeding | 25 |
Scitable Outline
Mitosis and Meiosis
Mitosis and Cell Division
Meiosis, Genetic Recombination, and Sexual Reproduction
Mendelian Genetics
Gregor Mendel and the Principles of Inheritance
Mendelian Genetics: Patterns of Inheritance and Single-Gene Disorders
Modifications of Mendelian Genetics
Discovery and Types of Genetic Linkage
Pleiotropy: One Gene Can Affect Multiple Traits
Epistasis: Gene Interaction and Phenotype Effects
Genetic Variation & Hardy-Weinberg Equilibrium
Sexual Reproduction and the Evolution of Sex
Neutral Theory: The Null Hypothesis of Molecular Evolution
HWE Violations: Natural Selection
Negative Selection
Natural Selection: Uncovering Mechanisms of Evolutionary Adaptation to Infectious Disease
HWE Violations: Mutation
Genetic Mutation
HWE Violations: Drift
Genetic Drift and Effective Population Size
Genetic Drift: Bottleneck Effect and the Case of the Bearded Vulture
HWE Violations: Gene Flow
Hybridization and Gene Flow
Why Should We Care about Species?
