Adams

Topics may not fit exactly in the time slots listed. To access the Scitable readings, look at the hand out you received at the first class for details.

The PDF files contain a copy of the slides used in lecture.

The lab titles are linked to PDF handouts for each of the labs.


Date
Topic
Text
Scitable
Slides
Lab ( Tuesdays)
Jan 18 W
Introduction      

 

 

Techniques

Using Spec 20 micropipettes

 

 

Library. Writing

 

 

DNA extraction

 

Protein synthesis

 

Lac operon

 

 

Restriction digests

 

 

Lab Exam

20 F
History. Genes are DNA 14.1, 4 1.1, 1.2, 1.3
23 M
DNA structure I 14 2.1
25 W
No class      
27 F
DNA Structure II, 14 2.2
30 M
Genome structure. RNA 14 2.3, 2.4
Feb 1 W
DNA Replication I 14 3.4, 3.1
3 F
DNA Replication II, Telomeres 14 3.2, 3.3
6 M
Gene Function 15 4.1, 4.2
8 W
Genetic Code 15 4.3, 4.4
10 F
Transcription I 16 5.1
13 M
Transcription II 16 5.2, 5.3
15 W
Exam I.      
17 F
Vacation      
20 M
Vacation      
22 W
Translation I 16 6.1, 6.2
24 F
Translation II 16 6.3, 6.4
27 M
Regulation I 17 7.1, 7.2
29 W
Regulation II 18 7.3
Mar 2 F
Mutation/Repair 14.5 8.1, 8.2, 8.3
5 M
Biotechnology I 19/20 9.1, 9.2, 9.5
7 W
Biotechnology II 19/20 9.3, 9.4, 9.6
16 F
Exam II    

 

 

Scitable readings

1.1 Introduction: What Is DNA?
1.2 Discovery of the Function of DNA Resulted from the Work of Multiple Scientists
1.3 Developing the chromosome theory

2.1 DNA is a structure that encodes biological information

2.2 Discovery of the function of DNA

2.3 Chemical structure of RNA

2.4 DNA packaging

3.4 DNA replication: overview

3.2 Semi-conservative DNA replication

3.2 Major molecular events of DNA replication

3.3 Telomeres and telomerase

4.1 Discovering the relationship between DNA and protein

4.2 Reading the genetic code

4.3 What is a gene?

4.4 Nucleic acids to amino acids

5.1 DNA transcription

5.2 RNA transcription by RNA polymerase

5.3 RNA splicing

6.1 Translation: DNA to mRNA to protein

6.2 The role of ribosomes

6.3 Translation

6.4 Protein folding

7.1 Overview

7.2 Negative transcription regulation

7.3 Positive transcription control

8.1 DNA replication and causes of mutation

8.2 Genetic mutation

8.3 Environmental mutagens

9.1 Plasmids

9.2 Restriction enzymes

9.3 Recombinant DNA

9.4 Animal cloning

9.5 Cell culture

9.6 Gene-based therapeutics

 

 

 

 

 

 

 

 

 

Szczys

Date Topic Lab Scitable
Mar 9 Cell Division- Mitosis    
12 Cell Division-Meiosis Mitosis and Meiosis Mitosis, Meiosis, and Inheritance
14 Mendel
16 Adams Exam 2
26 Mendelian Genetics Probability and Mendelian Genetics Sexual Reproduction and the Evolution of Sex
28 Hardy-Weinberg
30 Hardy-Weinberg
Apr 2 Natural Selection DNA extraction and PCR Evolutionary Adaptatin in Humans
4 Exam 3
9 Natural Selection
11 Natural Selection Gel Electrophoresis  
13 Natural Selection
16  Gene Flow
18 Gene Flow Comprehensive Exam Genetic Drift and Effective Population Size
20 Genetic Drift
23 Genetic Drift
25 Drift/Mutation Population structure Genetic Mutation
27 Mutation
30 Inbreeding
May 2 Inbreeding Inbreeding Why Should We Care About Species?
   
11 Final exam    

Scitable Outline

 

Mitosis and Meiosis

              Mitosis and Cell Division

Meiosis, Genetic Recombination, and Sexual Reproduction

Mendelian Genetics

              Gregor Mendel and the Principles of Inheritance

              Mendelian Genetics: Patterns of Inheritance and Single-Gene Disorders

Modifications of Mendelian Genetics

              Discovery and Types of Genetic Linkage

              Pleiotropy: One Gene Can Affect Multiple Traits

              Epistasis: Gene Interaction and Phenotype Effects

Genetic Variation & Hardy-Weinberg Equilibrium

              Sexual Reproduction and the Evolution of Sex

              Neutral Theory: The Null Hypothesis of Molecular Evolution

HWE Violations: Natural Selection

              Negative Selection

Natural Selection: Uncovering Mechanisms of Evolutionary Adaptation to Infectious Disease

HWE Violations: Mutation

              Genetic Mutation

HWE Violations: Drift

              Genetic Drift and Effective Population Size

              Genetic Drift: Bottleneck Effect and the Case of the Bearded Vulture

HWE Violations: Gene Flow

              Hybridization and Gene Flow

              Why Should We Care about Species?