Adams

Topics may not fit exactly in the time slots listed. To access the Scitable readings, look at the hand out you received at the first class for details.

'Slides' links to PDF files that contain a copy of the slides used in lecture.

The lab titles are linked to PDF handouts for each of the labs. (* Full lab report for this lab)

 

NOTE: Each chapter in the book has additional readings listed on the right hand side of each page. You are expected to read these, in addition to the basic information.

Spring 2014 schedule


Date
Topic
Text
Scitable
Slides
Lab ( Tuesdays)
Jan 13 M
Introduction, History 45,13  

 

 

 

Spec 20 and micropipettes

 

 

 

Library,Writing

 

 

 

DNA extraction

 

 

 

 

Flagella regeneration *

 

 

 

Lac operon

 

 

 

Restriction digests

 

 

 

Lab Exam
15 W
DNA structure I 45,13 1.1, 1.2, 1.3
17 F
DNA Structure II, 45,13 2.1
20 M
No class      
22 W
Genome structure 48, 63 2.2
24 F
DNA Replication I 48 2.3, 2.4
27 M
DNA Replication II, Telomeres 46,3 3.4, 3.1
29 W
Gene Function 49 3.2, 3.3
16 M
Genetic Code 49 4.1, 4.2
Feb  3 M
RNA 50,62 4.3, 4.4
5 W
Transcription I 50 5.1
7 F
Transcription II 50 5.2, 5.3
10 M
Translation I 51 6.1, 6.2
12 W
Exam I    
14 F
No class      
17 M
No class      
19 W
Translation II 52 6.3, 6.4
21 F
Regulation I 53,54 7.1, 7.2
24 M
Regulation II 51 7.3
26 W
Mutation 52 8.1,8.2
28 F
Repair 53,54 8.3
Mar  3 M
Biotechnology I 58,59 9.1, 9.2
5 W
Biotechnology II 60,61 9.3,9.4
7 F
Biotechnology III 61,62 9.5,9.6
14 F
Exam II    

 

 

Scitable readings

1.1 Introduction: What Is DNA?
1.2 Discovery of the Function of DNA Resulted from the Work of Multiple Scientists
1.3 Developing the chromosome theory

2.1 DNA is a structure that encodes biological information

2.2 Discovery of the function of DNA

2.3 Chemical structure of RNA

2.4 DNA packaging

3.4 DNA replication: overview

3.2 Semi-conservative DNA replication

3.2 Major molecular events of DNA replication

3.3 Telomeres and telomerase

4.1 Discovering the relationship between DNA and protein

4.2 Reading the genetic code

4.3 What is a gene?

4.4 Nucleic acids to amino acids

5.1 DNA transcription

5.2 RNA transcription by RNA polymerase

5.3 RNA splicing

6.1 Translation: DNA to mRNA to protein

6.2 The role of ribosomes

6.3 Translation

6.4 Protein folding

7.1 Overview

7.2 Negative transcription regulation

7.3 Positive transcription control

8.1 DNA replication and causes of mutation

8.2 Genetic mutation

8.3 Environmental mutagens

9.1 Plasmids

9.2 Restriction enzymes

9.3 Recombinant DNA

9.4 Animal cloning

9.5 Cell culture

9.6 Gene-based therapeutics

 

 

 

 

 

 

 

 

 

Szczys

 

 

 

 

Lab handouts

Mitosis/Meiosis

Probability

Computer Fly Lab

 

Scitable Outline

 

Mitosis and Meiosis

              Mitosis and Cell Division

Meiosis, Genetic Recombination, and Sexual Reproduction

Mendelian Genetics

              Gregor Mendel and the Principles of Inheritance

              Mendelian Genetics: Patterns of Inheritance and Single-Gene Disorders

Modifications of Mendelian Genetics

              Discovery and Types of Genetic Linkage

              Pleiotropy: One Gene Can Affect Multiple Traits

              Epistasis: Gene Interaction and Phenotype Effects

Genetic Variation & Hardy-Weinberg Equilibrium

              Sexual Reproduction and the Evolution of Sex

              Neutral Theory: The Null Hypothesis of Molecular Evolution

HWE Violations: Natural Selection

              Negative Selection

Natural Selection: Uncovering Mechanisms of Evolutionary Adaptation to Infectious Disease

HWE Violations: Mutation

              Genetic Mutation

HWE Violations: Drift

              Genetic Drift and Effective Population Size

              Genetic Drift: Bottleneck Effect and the Case of the Bearded Vulture

HWE Violations: Gene Flow

              Hybridization and Gene Flow

              Why Should We Care about Species?